Orphaned Help File Entries
If you uninstall the application or delete the help file the registry help file path entry becomes orphaned – i.e. it refers to a file that no longer exists. Such orphaned help file entries are completely useless and can be safely deleted.
Activating this option tells Registry Optimizer to find such orphaned help file entries so that you can delete them.
Note: The actual paths to the help files are often valid even though the files themselves no longer exist.